Publications

Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state

Semra Smajić, Cesar A Prada-Medina, Zied Landoulsi, Jenny Ghelfi, Sylvie Delcambre, Carola Dietrich, Javier Jarazo, Jana Henck, Saranya Balachandran, Sinthuja Pachchek, Christopher M Morris, Paul Antony, Bernd Timmermann, Sascha Sauer, Sandro L Pereira, Jens C Schwamborn, Patrick May, Anne Grünewald, Malte Spielmann
Brain. 2022 Apr 29;145(3):964-978. doi: 10.1093/brain/awab446.
https://pubmed.ncbi.nlm.nih.gov/34919646/

Nanopore Single-Molecule Sequencing for Mitochondrial DNA Methylation Analysis: Investigating Parkin-Associated Parkinsonism as a Proof of Concept

Theresa Lüth, Kobi Wasner, Christine Klein, Susen Schaake, Ronnie Tse, Sandro L Pereira, Joshua Laß, Lasse Sinkkonen, Anne Grünewald, Joanne Trinh
Front Aging Neurosci. 2021 Sep 28;13:713084. doi: 10.3389/fnagi.2021.713084. eCollection 2021.
https://pubmed.ncbi.nlm.nih.gov/34650424/

The Contribution of Microglia to Neuroinflammation in Parkinson’s Disease

Katja Badanjak, Sonja Fixemer, Semra Smajić, Alexander Skupin, Anne Grünewald
Int J Mol Sci. 2021 Apr 28;22(9):4676. doi: 10.3390/ijms22094676.
https://pubmed.ncbi.nlm.nih.gov/33925154/

Contemporary functional neuroanatomy and pathophysiology of dystonia

Brüggemann, N.
J Neural Transm (Vienna). 2021 Apr;128(4):499-508. doi: 10.1007/s00702-021-02299-y. Epub 2021 Jan 24.
https://pubmed.ncbi.nlm.nih.gov/33486625/

Genotype-driven therapeutic developments in Parkinson’s disease

Jannik Prasuhn, Norbert Brüggemann
Mol Med. 2021 Apr 19;27(1):42. doi: 10.1186/s10020-021-00281-8.
https://pubmed.ncbi.nlm.nih.gov/33874883/

Dystonia updates: definition, nomenclature, clinical classification, and etiology

Grütz K, Klein C
J Neural Transm (Vienna). 2021 Apr;128(4):395-404. doi: 10.1007/s00702-021-02314-2. Epub 2021 Feb 19.
https://pubmed.ncbi.nlm.nih.gov/33604773/

Truncating VPS16 Mutations Are Rare in Early Onset Dystonia

Pott H, Brüggemann N, Reese R, Zeuner KE, Gandor F, Gruber D, DysTract Studiengruppe; Klein C, Volkmann J, Lohmann K
Ann Neurol. 2021 Mar;89(3):625-626. doi: 10.1002/ana.25990. Epub 2020 Dec 28.
https://pubmed.ncbi.nlm.nih.gov/33305852/

Dystonia updates: definition, nomenclature, clinical classification, and etiology

Grütz K, Klein C
J Neural Transm (Vienna). 2021 Apr;128(4):395-404. doi: 10.1007/s00702-021-02314-2. Epub 2021 Feb 19.
https://pubmed.ncbi.nlm.nih.gov/33604773/

The importance of genetic testing for dystonia patients and translational research

Pozojevic J, Beetz C, Westenberger A
J Neural Transm (Vienna). 2021 Apr;128(4):473-481. doi: 10.1007/s00702-021-02329-9. Epub 2021 Apr 19.
https://pubmed.ncbi.nlm.nih.gov/33876307/

Functional and Molecular Properties of DYT-SGCE Myoclonus-Dystonia Patient-Derived Striatal Medium Spiny Neurons

Anna Kutschenko, Selma Staege, Karen Grütz, Hannes Glaß, Norman Kalmbach, Thomas Gschwendtberger, Lisa M Henkel, Johanne Heine, Anne Grünewald, Andreas Hermann, Philip Seibler, Florian Wegner
Int J Mol Sci. 2021 Mar 30;22(7):3565. doi: 10.3390/ijms22073565.
https://pubmed.ncbi.nlm.nih.gov/33808167/

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