Publications

Genome editing in induced pluripotent stem cells rescues TAF1 levels in X-linked dystonia-parkinsonism

Rakovic A, Domingo A, Grütz K, Kulikovskaja L, Capetian P, Cowley SA, Lenz I, Brüggemann N, Rosales R, Jamora D4, Rolfs A, Seibler P, Westenberger A, König I, Klein C.
Mov Disord. 2018 Jul;33(7):1108-1118. doi: 10.1002/mds.27441.
https://www.ncbi.nlm.nih.gov/pubmed/30153385

Genotype-Phenotype Relations for the Parkinson’s Disease Genes Parkin, PINK1, DJ1: MDSGene Systematic Review

Kasten M, Hartmann C, Hampf J, Schaake S, Westenberger A, Vollstedt EJ, Balck A, Domingo A, Vulinovic F, Dulovic M, Zorn I, Madoev H, Zehnle H, Lembeck CM, Schawe L, Reginold J, Huang J, König IR, Bertram L, Marras C, Lohmann K, Lill CM, Klein C.
Mov Disord. 2018 May;33(5):730-741. doi: 10.1002/mds.27352. Epub 2018 Apr 11.
https://www.ncbi.nlm.nih.gov/pubmed/29644727

Age- and sex-related heterogeneity in prodromal Parkinson’s disease

Heinzel S, Kasten M, Behnke S, Vollstedt EJ, Klein C, Hagenah J, Pausch C, Heilmann R, Brockmann K, Suenkel U, Yilmaz R, Liepelt-Scarfone I, Walter U, Berg D.
Mov Disord. 2018 Jul;33(6):1025-1027. doi: 10.1002/mds.27349. Epub 2018 Mar 23.
https://www.ncbi.nlm.nih.gov/pubmed/29570852

MDSGene: Closing Data Gaps in Genotype-Phenotype Correlations of Monogenic Parkinson’s Disease

Klein C, Hattori N, Marras C.
J Parkinsons Dis. 2018;8(s1):S25-S30. doi: 10.3233/JPD-181505.
https://www.ncbi.nlm.nih.gov/pubmed/30584170

Environmental and Genetic Variables Influencing Mitochondrial Health and Parkinson’s Disease Penetrance

Klein C, Hattori N, Marras C.
J Parkinsons Dis. 2018;8(s1):S25-S30. doi: 10.3233/JPD-181505.
https://www.ncbi.nlm.nih.gov/pubmed/30584170

Genome-Edited, TH-expressing Neuroblastoma Cells as a Disease Model for Dopamine-Related Disorders: A Proof-of-Concept Study on DJ-1-deficient Parkinsonism

Jannik Prasuhn, Christoph U. Mårtensson, Victor Krajka, Christine Klein,* and Aleksandar Rakovic.
Front Cell Neurosci. 2017; 11: 426. Published online 2018 Jan 8. doi: 10.3389/fncel.2017.00426
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770810/

Reduced penetrance of Leucine-rich repeat kinase 2 mutations: Discovering genetic factors of endogenous disease protection

Balck A, Klein C.
Mov Disord. 2017 Apr;32(4):527. doi: 10.1002/mds.26940. Epub 2017 Feb 20.
https://www.ncbi.nlm.nih.gov/pubmed/28218415

GCH1 mutations are common in Serbian patients with dystonia-parkinsonism: Challenging previously reported prevalence rates of DOPA-responsive dystonia

Dobričić V, Tomić A, Branković V, Kresojević N, Janković M, Westenberger A, Rašić VM, Klein C, Novaković I, Svetel M, Kostić VS.
Parkinsonism Relat Disord. 2017 Dec;45:81-84. doi: 10.1016/j.parkreldis.2017.09.017. Epub 2017 Sep 18.
https://www.ncbi.nlm.nih.gov/pubmed/28958832

Dystonia-causing mutations in the transcription factor THAP1 disrupt HCFC1 cofactor recruitment and alter gene expression

Hollstein R, Reiz B, Kötter L, Richter A, Schaake S, Lohmann K, Kaiser FJ.
Hum Mol Genet. 2017 Aug 1;26(15):2975-2983. doi: 10.1093/hmg/ddx187.
https://www.ncbi.nlm.nih.gov/pubmed/28486698

Scroll to Top