The DFG Research Unit 2488 “Reduced penetrance in hereditary movement disorders: elucidating mechanisms of endogenous disease protection” has now been successfully completed, and the final audit of the Research Unit has been concluded. We warmly thank the German Research Foundation (DFG) for its generous support and continued trust in our work. Our sincere gratitude also goes to all researchers, clinicians, technical and administrative staff, collaborating institutions in Germany and abroad, as well as to the patients and their families, whose commitment and support have been essential for the success of this research.