The Institute of Neurogenetics is happy to welcome visiting professor Prof. Dr. M. Leonor Bustamante

We are delighted to welcome Professor M. Leonor Bustamante, joining the Institute of Neurogenetics in Lübeck as a Visiting Professor for this month. M. Leonor Bustamante, MD, Ph.D. is an Assistant Professor at the Human Genetics Program, Biomedical Sciences Institute, Faculty of Medicine at the Universidad de Chile.
She works on Genetics of Neuropsychiatric disorders, where she, together with her team, contributes to the Monogenic Hub of the GP2 (Global Parkinson’s Genetics Program) that Professor Klein leads.

Lecture by Prof. Dr. Rifat Hamoudi on his paper: Enriched transcriptome analysis of laser capture microdissected populations of single cells to investigate intracellular heterogeneity in immunostained FFPE sections.

Upcoming Meeting and Progress Report of FOR 2488 December 2nd-3rd, 2021

Lecture by Prof. Dr. Thomas Gasser on Genetic risk variants and Parkinson’s disease.

During our annual retreat FOR 2488 from September 16th to 18th, Prof. Thomas Gasser from the University of Tübingen honored us with his first keynote lecture after 1.5 years on “Genetic risk variants and Parkinson’s disease.”

FOR 2488’s Annual Retreat took place from September 16th-18th, 2021 in Lübeck, Germany. During the two-day event, participants gathered to exchange and discuss data and research ideas, as well as establish new collaborative initiatives.

Clinical Neuroscience Grand Rounds | Upcoming Talk by Prof. Dr. Christine Klein, Parkinson’s disease genetics: Cause or risk? on April 27, 2021

February 17, 2021

Prof. Christine Klein has been re-elected for another three years to serve on the Heinz-Maier-Leibnitz Prize Selection Committee of the DFG

February 17, 2021

Prof. Dr. rer. nat. Jeanette Erdmann appointed as member of the Permanent Senate Commission of the German Research Foundation (DFG)

February 4, 2021

The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) has appointed Prof. Dr. rer. nat. Jeanette Erdmann as a member of the Permanent Senate Commission on Basic Questions in Genetic Research.

Jeanette Erdmann studied biology in Cologne and completed her doctoral thesis at the Institute of Human Genetics in Bonn. After her doctorate, she worked as a research group leader in Berlin and Regensburg. She completed her habilitation at the University of Regensburg. Since 2003, she has been working at the University of Lübeck. In 2012, she was appointed DZHK professor for life. Since 2013, she has successfully led the newly founded Institute of Cardiogenetics, which aims to better understand the genetic factors that lead to cardiovascular diseases, e.g., atherosclerosis and myocardial infarction.

The Permanent Senate Commission on Genetic Research advises the DFG’s Executive Committee and Senate, but also – in accordance with the DFG’s statutory mandate – parliaments and authorities on issues relating to genetic research, genetic engineering and their effects. The Permanent Senate Commission on Genetic Research thus deals with areas in which research policy tasks exist, where there are deficits in the discussion and where developments in genetic research are apparent that raise scientific, ethical, legal and social questions.

The Commission consists of scientists from various German universities. The Commission was founded in 1994 and has issued statements on predictive genetic diagnostics and recommendations on human stem cell research, among other things.

Research Unit Meeting | 1st Quarter 2021

Planned Research Unit meeting taking place on January 28th and February 1st, 2020. We are looking forward to an exciting review of new data and fruitful discussions of our projects and future perspectives.

Z2 Research Unit Team Meeting (January 14, 2021)

Doctors take the lead for patients | Frankfurter Allgemeine Zeitung special edition

 November 4, 2020

“Doctors take the lead for patients”

Economization is presenting physicians with challenges and conflicts. ‘Reimagine Medicine’ aims to initiate a movement for change through a broad dialogue. Christine Klein and Peter P. Pramstaller talk about this project and about concrete measures to support physicians.

To read the whole article (in German), please click on the following link.

DFG funds research group ProtectMove for another three years

The research group “ProtectMove – reduced penetrance in hereditary movement disorders: Elucidation of Mechanisms of Endogenous Disease Protection” at the University of Lübeck is funded by the German Research Foundation (DFG) for a further three years. This decision was made by the Joint Committee of the DFG at its meeting during the Annual General Meeting on 1 July 2020. The spokesperson of the Research Unit, which has been in existence since 2016, is Prof. Dr. Christine Klein, Head of the University’s Institute of Neurogenetics.

On August 1st, 2019, the Deputy CEO of The Michael J. Fox Foundation, Sohini Chowdhury, visited the Institute of Neurogenetics

Anne Weißbach awarded with the David Marsden Award 2019

Dr. med. Anne Weißbach from the Institute of Neurogenetics at the University of Lübeck was awarded the David Marsden Award 2019 for her research.

The Dystonia Europe Prize, which has been awarded every two years since 2003, is named after David Marsden (1938-1998), one of the leading European neurologists of his time. The Marsden Award is intended to promote research by young scientists in the field of neurological movement disorders.

Dr. Joanne Trinh was invited to the Humboldt Annual Meeting where Chancellor Angela Merkel gave a speech to fellow Humboldtians and a celebration of Alexander Von Humboldt’s 250th birthday at the schloss Bellevue where President Steinmeier lives.

Victor Krajka received a short-term fellowship for his research stay with Dr. Carsten Janke at the Institut Curie in Orsay, France.

Multimodal field study in the Philippines

Field study in the Philippines investigating affected and unaffected carriers of the X-linked dystonia-parkinsonism (XDP) mutation to study penetrance and expressivity of XDP as part of a CCXDP Project and DFG FOR2488.

Talk by Prof. Hyder (Buz) Jinnah, Emory University: Genotype-Phenotype Correlations in Neurological Disease.

The talk will take place in the Audimax, Seminar Room AM S2 in Lübeck, on May 8th from 12 – 1 pm.

H. A. (Buz) Jinnah is at Emory University in Atlanta where he is Professor of Neurology and Human Genetics.  He has a clinical practice and research program devoted to all types dystonia, with a particularly interest in neurogenetic disorders.  He has published more than 200 articles addressing a variety of topics including genetics and biochemistry, cell biology, anatomy and histopathology, and clinical and translational studies.

He has given over 100 invited lectures internationally.  He currently is Chair of the Program Planning Committee of the meeting for the International Parkinson’s Disease and Movement Disorders Society, and director of the Dystonia Coalition, an initiative funded by the NIH to stimulate clinical and translational research for the isolated dystonias, with more than 40 collaborating institutions from several countries across North America, Europe, and Australia.

Retreat of FOR2488

The retreat of research group FOR2488 took place in Bolzano, Italy between April 8th-9th, 2019.

Reduced Penetrance Conference in Lübeck

During the two-day conference (10-11 December) nearly 120 participants came together to share and discuss data and research ideas and to set up new collaborative efforts related to reduced penetrance.

X-linked dystonia-parkinsonism workshop at the Institute of Neurogenetics

The Institute of Neurogenetics and the Movement Disorder Society of the Philippines (MDSP) recently (September 19-21, 2018) organized an X-linked dystonia-parkinsonism workshop in Luebeck.

Topics covered in the workshop included clinical assessment, therapeutic strategies, and functional and molecular neurogenetics. The MDSP also hosted an XDP awareness drive for the Filipino communities in Luebeck and Hamburg.

The Michael J. Fox Foundation awarded an Edward J. Safra Fellowship to the Institute of Neurogenetics. Anne Weissbach, MD is the recipient of this prestigious career development award.

To download the article, click here.

Charles Jourdan Reyes has been awarded a Ph.D. scholarship (Program 2) by the Catholic Academic Exchange Service (KAAD)

The scholarship is given to advanced international students from developing countries to help them reintegrate to their home countries after their graduate studies in Germany. Charles is currently doing research on genetic modifiers of disease penetrance and expressivity in X-linked dystonia-parkinsonism under the supervision of PD Dr. Ana Westenberger.

Congratulations to Kobi Wasner for the SfN 2018 Trainee Professional Development Award (TPDA)

Kobi Wasner

PhD candidate Kobi Wasner from the Molecular and Functional Neurobiology Group at the Luxembourg Centre for Systems Biomedicine, has received the “2018 Trainee Professional Development Award (TPDA)” from the Society for Neuroscience for his project entitled: “Investigating a novel role for parkin in mitochondrial DNA maintenance in induced pluripotent stem cell-derived neurons from Parkinson’s disease patients.”

New group on’integrative omics approaches

A junior research group under the Translational Neurogenetics Section has been formed to spearhead genetic and genomic approaches including genome sequencing, deep mito-sequencing, RNA sequencing and epigenetics to identify highly penetrant mutations, risk factors and disease modifying genetic variants in Parkinson’s disease. One focus of this research group will be on genetic modifiers of reduced penetrance, which will strengthen the Research Unit.


The Institute of Neurogenetics is happy to announce the new website launch for the ‘Reduced Penetrance Conference’ 2018.

For more information please visit

2018 Interim Meeting of the Protect Move Research Unit.

Thursday, July 5th, 2018 .


Center of Brain, Behavior and Metabolism (CBBM)
2nd Floor, Room 5
Universität zu Lübeck, Geb. 66
Ratzeburger Allee 160

23562 Lübeck

To download the agenda, please click here.

Source: Institute of Neurogenetics

Jannik Prasuhn has been awarded 200.000US$ of the Parkinson’s Foundation Clinical Research Award.

Melissa Vos meeting Nobel Laureate Yoshinori Ohsumi at the Lindau Laureate Meeting.

Once every year, about 30 Nobel Laureates convene in Lindau, Germany, to meet the next generation of leading scientists.

Around 600 students and post-docs from all over the world gather together for a week and get the chance to meet and discuss with the Laureates during lunches, walks and talks.

Here, Melissa Vos is having lunch with Prof. Yoshinori Ohsumi who won the price for medicine in 2016 for his discovery of the autophagy process.

Source: Institute of Neurogenetics

Dr. Sammler’s research interests include accelerating the application of scientific discoveries via target validation to facilitate the development of biomarkers and novel treatments.

Source: Institute of Neurogenetics

Kobi Wasner has joined the Institute of Neurogenetics as a visiting scientist.

Kobi Wasner from the University of Luxembourg has joined the Institute of Neurogenetics for a three-month internship, starting from April 2018.

Kobi completed his Bachelor’s degree at Queens College in New York City in Neuroscience and Psychology. He then went on to complete a Master’s degree at the University of Connecticut Health Center, where he learned to work with induced pluripotent stem cells (iPSCs).

We are enthusiastic to have him as an intern and welcome him at our institute.

Source: Institute of Neurogenetics

ProtectMove 2017 Progress Report

First Interim Meeting of the Protect Move Research Unit coming up


December 11 – 12, 2017


Institute of Neurogenetics
Maria-Goeppert-Straße 1

23562 Lübeck

To download the agenda, please click here.

The German Academy for Rare Neurological Diseases (Deutsche Akademie für Seltene Neurologische Erkrankungen; DASNE) celebrates its foundation. The event takes place at the Wartburg castle in Eisenach, Germany from November 29th until December 1st. Being the first institution in the area of rare diseases, the DASNE sees itself as a network for bundling expertise with the goal of better patient care.

For more information, please visit

Christine Klein was awarded a new research grant from The Michael J. Fox Foundation for Parkinson’s Research (MJFF) for the project entitled Identifying global cohorts with monogenic Parkinson’s disease.

Christine Klein awarded the Movement Disorder Society’s Distinguished Service Award in Vancouver, Canada on June 4th, 2017

Philip Seibler appointed W2 Professor for Applied Stem Cell Research

Dr. Joanne Trinh has joined the Institute of Neurogenetics as a postdoctoral research fellow.

headshot14.02.2017 – Dr. Joanne Trinh has joined the Institute of Neurogenetics as a postdoctoral research fellow. She completed her PhD studies in genetic modifiers of disease onset in LRRK2 parkinsonism at the University of British Columbia with Prof. Dr. Matthew Farrer ( Her passion for identifying factors that influence onset age of Parkinson disease has led her to join the ‘Reduced Penetrance in Hereditary Movement Disorders – ProtectMove’ DFG Research Unit. She aspires to strengthen the research unit with her expertise in genetics and genomics of penetrance modifiers. We are enthusiastic to have her on the team!

Kick-Off Meeting


December 19th, 2016


Institute of Neurogenetics
Maria-Goeppert-Straße 1

23562 Lübeck