Position/Title: Director (Institute of Medical Informatics and Statistics), W3 Professor

Address Christian-Albrechts University of Kiel; Brunswiker Straße 10, 24105 Kiel, Germany

Tel: +49-431-5973201; Fax: +49-431-5973193

@: mailto:krawczak@medinfo.uni-kiel.de; www.uni-kiel.de/medinfo/institut/



1979-1984 Studies of Mathematics and National Economics (Göttingen, Germany)

1984-1987 Doctoral Training in Developmental Biology (Institute of Human Genetics, Göttingen)

1987 PhD in Developmental Biology (Göttingen)

1987-1991 Postdoctoral researcher, Institute of Human Genetics, Göttingen

1991-1996 Senior Research Scientist, Institute of Human Genetics, Medizinische Hochschule Hannover, Germany

1995 Habilitation (Human Genetics)

1996-2000 DFG Heisenberg Professorship, Institute of Medical Genetics, University of Wales College of Medicine, Cardiff, UK

2000-2001 Professor of Mathematical Genetics, University of Wales College of Medicine, Cardiff, UK

2002-present Full Professor of Medical Informatics and Statistics (C4, since 2012: W3)

2001-present Director Institute of Medical Informatics and Statistics, Christian-Albrechts University of Kiel

2001 Offer: Professorship of Genetic Epidemiology (C3), University of Ulm (declined)

2012 Offer: Professorship of Medical Informatics and Statistics (W3), Rhenish Friedrich-Wilhelms University of Bonn (declined)



1996-2012 Scientific Advisory Board, German Society of Human Genetics

1998-present Editorial Board, Human Genetics

2001-2008 Editorial Board, Pharmacogenetics

2006-2019 Section Editor, Encyclopedia of Life Sciences

2007-present Member, Board of Directors, Technologie- und Methodenplattform für die Medizinische Forschung TMF e.V. Berlin, Germany

2008-present Member, Board of Directors, Schleswig-Holsteinsche Universitätsgesellschaft, Kiel, Germany

2010-2017 Editorial Board, Investigative Genetics

2011-present Chairman, Board of Directors, TMF e.V.

2012-2017 Section Editor, Journal of Community Genetics

2012-present Member, Habilitationskommission, Medical Faculty, Christian-Albrechts University of Kiel

2018-present Member, Forschungskommission, Medical Faculty, Christian-Albrechts University of Kiel



1996 Heisenberg Scholarship from the DFG


SELECTED PUBLICATIONS (from the last 5 years)

From 391 original publications; total citations: 21,856; h-index: 74

    1. Cooper DN, Krawczak M, Polychronakos C, Tyler-Smith C, Kehrer-Sawatzki H. Where genotype is not predictive of phenotype: towards an understanding of the molecular basis of reduced penetrance in human inherited disease. Hum Genet 2013;132:1077-1130. [IF: 4.5]
    2. Knecht C, Krawczak M. Molecular genetic epidemiology of human diseases: From patterns to predictions. Hum Genet 2014;133:425-430. [IF: 4.8]
    3. Yadav P, Freitag-Wolf S, Lieb W, Krawczak M. The role of linkage disequilibrium in case-only studies of gene-environment interactions. Hum Genet 2015;134:89-96. [IF: 4.8]
    4. Yadav P, Freitag-Wolf S, Lieb W, Dempfle A, Krawczak M. Allowing for population stratification in case-only studies of gene-environment interaction, using genomic control. Hum Genet 2015; 134: 1117-1125. [IF: 4.8]
    5. Knecht C, Mort M, Cooper DN, Krawczak M, Caliebe A. IMHOTEP – A composite score integrating popular tools for predicting the functional consequences of exonic DNA sequence variants. Nucleic Acids Res 2017;45:e13. [IF: 6.5]
    6. Bauer CRKD, Knecht C, Fretter C, Baum B, Jendrossek S, Rühlemann M, Heinsen FA, Umbach N, Grimbacher B, Franke A, Lieb W, Krawczak M, Hütt MT, Sax U. Interdisciplinary approach towards a systems medicine toolbox using the example of inflammatory Brief Bioinform 2017; 18: 479-487. [IF: 6.3]
    7. Yadav P, Ellinghaus D, Rémy G, Freitag-Wolf S, Cesaro A, Degenhardt F, Boucher G, Delacre M, The International IBD Genetics Consortium (IIBDGC), Peyrin-Biroulet L, Pichavant M, Rioux JD, Gosset P, Franke A, Schumm LP, Krawczak M, Chamaillard M, Dempfle A, Andersen V. Genetic factors interact with tobacco smoke to modify risk for inflammatory bowel disease in humans and mice. Gastroenterol 2017; 153:550-565. [IF: 20.8]
    8. Richter G, Krawczak M, Lieb W, Wolff L, Schreiber S, Buyx A. Broad consent for healthcare-embedded biobanking: understanding and reasons to donate in a large patient sample. Genet Med 2018; 20: 76-82.           [IF: 8.7]
    9. Krawczak M, Budowle B, Weber-Lehmann J, Rolf B. Distinguishing genetically between the germlines of male monozygotic twins. PLoS Genet 2018; 14: e1007756. [IF: 5.2]
    10. Schlicht K, Nyczka P, Caliebe A, Freitag-Wolf S, Claringbould A, Franke L, Võsa U, BIOS Consortium, Kardia SLR, Smith JA, Zhao W, Gieger C, Peters A, Prokisch H, Strauch K, KORA Study Group, Baurecht H, Weidinger S, Rosenstiel P, Hütt MT, Knecht C, Szymczak S, Krawczak M. The metabolic network coherence of human transcriptomes is associated with genetic variation at the cadherin 18 locus. Hum Genet 2019; 138: 375-388. [IF: 5.2]