The figure above shows the interaction between the projects of the Research Unit. Projects P1-P8 all address different aspects of reduced penetrance in movement disorders with a focus on Parkinson’s disease (blue), monogenic dystonia (red), dystonia-parkinsonism (purple), dystonia in general (pink), or method development/analysis (gray). (A) Data from all projects are continuously provided by, and fed back to, the Central Cohort Project (Z2) and to the Central Knowledge Base (INF). Likewise, data from INF (both from the literature and own preliminary or newly generated) will inform additional queries to Z2; conversely, all available and newly collected data will further complement INF with similar feedback mechanisms to and from P1-P8. Z1 serves as central coordination project of the entire Research Unit. (B) In addition, there will be direct interactions between projects P1-P8.