Position/Title: Director (Institute of Medical Informatics and Statistics), W3 Professor

Address Christian-Albrechts University of Kiel; Brunswiker Straße 10, 24105 Kiel, Germany

Tel: +49-431-5973201; Fax: +49-431-5973193

@: mailto:krawczak@medinfo.uni-kiel.de; www.uni-kiel.de/medinfo/institut/



1979-1984 Studies of Mathematics and National Economics (Göttingen, Germany)

1984-1987 Doctoral Training in Developmental Biology (Institute of Human Genetics, Göttingen)

1987 PhD in Developmental Biology (Göttingen)

1987-1991 Postdoctoral researcher, Institute of Human Genetics, Göttingen

1991-1996 Senior Research Scientist, Institute of Human Genetics, Medizinische Hochschule Hannover, Germany

1995 Habilitation (Human Genetics)

1996-2000 DFG Heisenberg Professorship, Institute of Medical Genetics, University of Wales College of Medicine, Cardiff, UK

2000-2001 Professor of Mathematical Genetics, University of Wales College of Medicine, Cardiff, UK

2002-present Full Professor of Medical Informatics and Statistics (C4, since 2012: W3)

2001-present Director Institute of Medical Informatics and Statistics, Christian-Albrechts University of Kiel

2001 Offer: Professorship of Genetic Epidemiology (C3), University of Ulm (declined)

2012 Offer: Professorship of Medical Informatics and Statistics (W3), Rhenish Friedrich-Wilhelms University of Bonn (declined)



1996-2012 Scientific Advisory Board, German Society of Human Genetics

1998-present Editorial Board, Human Genetics

2001-2008 Editorial Board, Pharmacogenetics

2006-present Section Editor, Encyclopedia of Life Sciences

2007-present Member, Board of Directors, Technologie- und Methodenplattform für die Medizinische Forschung TMF e.V. Berlin, Germany

2008-present Member, Board of Directors, Schleswig-Holsteinsche Universitätsgesellschaft, Kiel, Germany

2010-present Editorial Board, Investigative Genetics

2011-present Chairman, Board of Directors, TMF e.V.

2012-present Section Editor, Journal of Community Genetics

2012-present Member, Habilitationskommission, Medical Faculty, Christian-Albrechts University of Kiel



1996 Heisenberg Scholarship from the DFG


SELECTED PUBLICATIONS (from the last 5 years)

From 344 original publications; total citations: 18,087; h-index: 68

  1. Nothnagel M, Lu TT, Kayser M, Krawczak M. Genomic and geographic distribution of SNP-defined runs of homozygosity in Europeans. Hum Mol Genet 2010;19:2927-2935. (IF: 6.7)
  2. Cooper DN, Chen JM, Ball EV, …, Krawczak M, …, Stenson PD. Genes, mutations, and human inherited disease at the dawn of the age of personalized genomics. Hum Mutat 2010;31:631-655. (IF: 5.1)
  3. Jochens A, Caliebe A, Rösler U, Krawczak M. Empirical evaluation of microsatellite mutation models for Y-chromosomal loci. Genetics 2011;189:1403-1411. (IF: 4.9)
  4. Wolf A, Caliebe A, Thomas NST, …, Krawczak M, Cooper DN. Single base-pair substitutions at the translational initiation sites of human genes as a cause of inherited disease. Hum Mutat 2011;10:1137-1143. (IF: 5.1)
  5. Nothnagel M, Wolf A, Herrmann A, …, Krawczak M. Statistical inference of allelic imbalance from transcriptome data. Hum Mutat 2011;32:98-106. (IF: 5.1)
  6. Fritsch C, Herrmann A, Nothnagel M, …, Krawczak M, …, Brosch M. Genome-wide search for novel human uORFs and N-terminal protein extensions using ribosomal footprinting. Genome Res 2012;22:2208-2218. (IF: 13.9)
  7. Cooper DN, Krawczak M, Polychronakos C, Tyler-Smith C, Kehrer-Sawatzki H. Where genotype is not predictive of phenotype: towards an understanding of the molecular basis of reduced penetrance in human inherited disease. Hum Genet 2013;132:1077-1130. (IF: 4.5)
  8. Knecht C, Krawczak M. Molecular genetic epidemiology of human diseases: From patterns to predictions. Hum Genet 2014;133:425-430. (IF: 4.5)
  9. Stade B, Seelow D, Thomsen I, Krawczak M, Franke A. GrabBlur – a framework to facilitate the secure exchange of whole-exome and -genome sequencing SNV data using VCF files. BMC Genomics 2014;15 Suppl 4:S8. (IF: 4.5)
  10. Yadav P, Freitag-Wolf S, Lieb W, Krawczak M. The role of linkage disequilibrium in case-only studies of gene-environment interactions. Hum Genet 2015;134:89-96. (IF: 4.0)