Position/Title: Head (Section for Functional Genetics at the institute for Human Genetics),

W3 Professor

Address University of Lübeck; Ratzeburger Allee 160, 23538 Lübeck, Germany

Tel: +49-451-50050411; Fax:+49-451-50050434




1993-1999 Biology (Ruhr-University of Bochum, Germany)

1999-2000 Diploma Thesis (Ag for Molecular Genetics, Bochum)

2000-2003 PhD training (Institute for Human Genetics, Essen, Germany; Laboratory of

Bernhard Horsthemke)

2003-2006   Research Fellow (Institute for Human Genetics, Essen, Germany)

2006-2008 Research group leader (Institute for Human Genetics, Lübeck, Germany)

2008-2014 Head of the molecular laboratory at the Institute for Human Genetics

2013-present Principal Investigator and member of the German Center for Cardiovascular Research (DZHK)

2013 Habilitation

2014-present Head of the newly founded Section for Functional Genetics, University of Lübeck



2001-present Member of the German Society of Human Genetics

2012-present Member of the European Society of Human Genetics

2012-2015 Board Member of the German Academy for Human Genetics (representative of the section for molecular genetics)

2013-present Member of the American Society of Human Genetics

2013-present Coordinator of the E-Rare European Research Network “TARGET-CdLS”

2014-present Member of the programme commission of the German society of Human Genetics

2014-present Member of the scientific advisory board of the CdLS foundation



2002 Winner of the first PhD/MD training award of the University of Duisburg

Essen (best poster and best oral presentation)

2007 Travel award of the German Society of Human Genetics

2007 Isabelle Oberlé Award of the European Society of Human Genetics

2011 Travel award of the International Conference for Human Genetics (ICHG, Montral Canada)

2012 Dr. Holger Müller Research Award (Care for Rare Foundation)



From 48 original publications; total citations: 1,141; h-index: 20

    1. Jahnke P, Xu W, Wülling M, …, Kaiser FJ. The Cohesin loading factor NIPBL recruits histone deacetylases to mediate local chromatin modifications. Nucleic Acids Res 2008;36:6450-6458. (IF: 8.8)
    1. Kaiser FJ, Osmanoric A, Rakovic A, …, Lohmann K. The dystonia gene DYT1 is repressed by the transcription factor THAP1 (DYT6). Ann Neurol 2010;68:554-559. (IF: 11.9)
    1. Osmanovic A, Dendorfer A, Erogullari A, …, Kaiser FJ. Truncating mutations in THAP1 define the nuclear localization signal. Mov Disord. 2011;26:1565-1567. (IF: 5.6)
    1. Lohmann K, Wilcox RA, Winkler S, …, Kaiser FJ, …, Klein C. Whispering dysphonia (DYT4 dystonia) is caused by a mutation in the TUBB4 gene. Ann Neurol. 2012;73:537-545. (IF: 11.9)
    1. Deardorff MA, Bando M, Nakato R, …, Kaiser FJ, …, Shirahige K. HDAC8 mutations in Cornelia de Lange Syndrome affect the cohesin acetylation cycle. Nature 2012;489:313-317. (IF: 42.4)
    1. Deardorff MA, Wilde JJ, Albrecht M, …, Kaiser FJ. RAD21 Mutations Cause a Human Cohesinopathy. Am J Hum Genet 2012;90:1014-1027. (IF: 11.0)
    1. Erdmann J, Stark K, Esslinger UB, …, Kaiser FJ, …, Schunkert H. Dysfunctional nitric oxide signalling increases risk of myocardial infarction. Nature 2013;504:432-436. (IF: 42.4)
    1. Miller CL, Haas U, Diaz R, …, Kaiser FJ, …, Sczakiel G. Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation. PLoS Genet 2014;10(3):e1004263. (IF: 8.2)
    1. Kaiser FJ, Ansari M, Braunholz D, … , Deardorff MA. Loss of Function HDAC8 Mutations Cause a Phenotypic Spectrum of Cornelia de Lange Syndrome-like Features, Ocular Hypertelorism, Large Fontanelle and X-linked Inheritance Hum Mol Genet 2014;23:2888-2900. (IF: 6.7)
    1. Braunholz D, Obieglo C, Parenti I, …, Kaiser FJ. Hidden mutations in Cornelia de Lange syndrome limitations of sanger sequencing in molecular diagnostics. Hum Mutat 2015;36:26-29. (IF: 5.1)