Age- and sex-related heterogeneity in prodromal Parkinson’s disease

Heinzel S, Kasten M, Behnke S, Vollstedt EJ, Klein C, Hagenah J, Pausch C, Heilmann R, Brockmann K, Suenkel U, Yilmaz R, Liepelt-Scarfone I, Walter U, Berg D.
Mov Disord. 2018 Jul;33(6):1025-1027. doi: 10.1002/mds.27349. Epub 2018 Mar 23.

https://www.ncbi.nlm.nih.gov/pubmed/29570852

MDSGene: Closing Data Gaps in Genotype-Phenotype Correlations of Monogenic Parkinson’s Disease

Klein C, Hattori N, Marras C.
J Parkinsons Dis. 2018;8(s1):S25-S30. doi: 10.3233/JPD-181505.

https://www.ncbi.nlm.nih.gov/pubmed/30584170

Environmental and Genetic Variables Influencing Mitochondrial Health and Parkinson’s Disease Penetrance

Alessandra Zanon, Peter P. Pramstaller, Andrew A. Hicks, and Irene Pichler corresponding author.
Parkinsons Dis. 2018; 2018: 8684906. Published online 2018 Mar 7. doi: 10.1155/2018/8684906

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863306/

Genome-Edited, TH-expressing Neuroblastoma Cells as a Disease Model for Dopamine-Related Disorders: A Proof-of-Concept Study on DJ-1-deficient Parkinsonism

Jannik Prasuhn, Christoph U. Mårtensson, Victor Krajka, Christine Klein,* and Aleksandar Rakovic.
Front Cell Neurosci. 2017; 11: 426. Published online 2018 Jan 8. doi: 10.3389/fncel.2017.00426
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770810/

Reduced penetrance of Leucine-rich repeat kinase 2 mutations: Discovering genetic factors of endogenous disease protection

Balck A, Klein C.
Mov Disord. 2017 Apr;32(4):527. doi: 10.1002/mds.26940. Epub 2017 Feb 20.
https://www.ncbi.nlm.nih.gov/pubmed/28218415

GCH1 mutations are common in Serbian patients with dystonia-parkinsonism: Challenging previously reported prevalence rates of DOPA-responsive dystonia

Dobričić V, Tomić A, Branković V, Kresojević N, Janković M, Westenberger A, Rašić VM, Klein C, Novaković I, Svetel M, Kostić VS.
Parkinsonism Relat Disord. 2017 Dec;45:81-84. doi: 10.1016/j.parkreldis.2017.09.017. Epub 2017 Sep 18.
https://www.ncbi.nlm.nih.gov/pubmed/28958832

Dystonia-causing mutations in the transcription factor THAP1 disrupt HCFC1 cofactor recruitment and alter gene expression

Hollstein R, Reiz B, Kötter L, Richter A, Schaake S, Lohmann K, Kaiser FJ.
Hum Mol Genet. 2017 Aug 1;26(15):2975-2983. doi: 10.1093/hmg/ddx187.
https://www.ncbi.nlm.nih.gov/pubmed/28486698

What would Dr. James Parkinson think today? The role of genetics in Parkinson’s disease

Lill CM, Klein C.
Mov Disord. 2017 Aug;32(8):1115-1116. doi: 10.1002/mds.27141.
https://www.ncbi.nlm.nih.gov/pubmed/28836355

Influence of L-dopa on subtle motor signs in heterozygous Parkin- and PINK1 mutation carriers.

Weissbach A, König IR, Hückelheim K, Pramstaller PP, Werner E, Brüggemann N, Tadic V, Lohmann K, Bäumer T, Münchau A, Kasten M, Klein C.
Parkinsonism Relat Disord. 2017 Jul 8. pii: S1353-8020(17)30236-5. doi: 10.1016/j.parkreldis.2017.07.003. [Epub ahead of print] https://www.ncbi.nlm.nih.gov/pubmed/28716427

Complex and Dynamic Chromosomal Rearrangements in a Family With Seemingly Non-Mendelian Inheritance of Dopa-Responsive Dystonia

Lohmann K, Redin C, Tönnies H, Bressman SB, Subero JIM, Wiegers K, Hinrichs F, Hellenbroich Y, Rakovic A, Raymond D, Ozelius LJ, Schwinger E, Siebert R, Talkowski ME, Saunders-Pullman R, Klein C.
JAMA Neurol. 2017 Jul 1;74(7):806-812. doi: 10.1001/jamaneurol.2017.0666.
https://www.ncbi.nlm.nih.gov/pubmed/?term=28558098