Position/Title: Head (Albrecht-Kossel-Institute for Neuroregeneration), W3 Professor

Address University of Rostock; Gehlsheimerstr. 20, 18147 Rostock, Germany

Tel: +49-381-4949540; Fax: +49-381-4949542




1978 – 1985 Human Medicine (University of Mainz and Vienna)

1985 Approbation for human medicine

1985 Medical Thesis (University of Mainz)

1985-1991 Resident at the Department of Neurology and Department of Psychiatry, Free University Berlin

1991-1993 MPI for Molecular Genetics, Berlin (Prof. Dr. K Mölling)

1993 Consultant for Neurology and Psychiatry; Vice-Director at the Department of Neurology, University of Rostock

1995 Habilitation

1997 Tenure track professorship (C3-Professor) for clinical Neurology

Since 1998 Principal investigator of several international multicenter studies in the area of rare diseases (e.g. sifap-project; world largest study in young stroke patients;

Since 2008 Director (W3) of Albrecht-Kossel-Institute, Medical Faculty, University Rostock



Since 1991 Consultant for more than 25 international biotech companies

2001 Co-founder of Arcensus AG (Berlin) and Genebanking AG (Berlin)



From 185 original publications; total citations: 4,176 ; h-index: 30

  1. Rolfs A, Böttcher T, Zschiesche M, …, Benecke R. High prevalence of Fabry disease in young stroke patients. Lancet 2005;366:1794-1796. (IF: 39.2)
  2. Sidransky E, Nalls MA, Aasly JO, …, Rolfs A, …, Ziegler SG. Multicenter analysis of glucocerebrosidase mutations in Parkinson’s disease. N Engl J Med 2009;361:1651-1661. (IF: 54.4)
  3. Rolfs A, Giese AK, Grittner U, …, Mascher H. Glucosylsphingosine Is a Highly Sensitive and Specific Biomarker for Primary Diagnostic and Follow-Up Monitoring in Gaucher Disease in a Non-Jewish, Caucasian Cohort of Gaucher Disease Patients. PLoS One 2013;8:e79732. (IF: 3.5)
  4. Böttcher T, Rolfs A, Meyer B, …, Walter U. Clinical, genetic, and brain sonographic features related to Parkinson’s disease in Gaucher disease. J Neurol 2013,260:2523–2531.
  5. Lukas J, Giese AK, Markoff A, …, Rolfs A. Functional Characterisation of Alpha-Galactosidase A Mutations as a Basis for a New Classification System in Fabry Disease. PLoS Genet 2013;9:e1003632. (IF: 8.2)
  6. von Sarnowski B, Schminke U, Tatlisumak T, …, Rolfs A; On behalf of the sifap1 investigators. Prevalence of stenoses and occlusions of brain-supplying arteries in young stroke patients. Neurology 2013;80:1287-1294. (IF: 8.3)
  7. Westenberger A, Rosales RL, Heinitz S, …, Rolfs A, …, Klein C. X-linked Dystonia-Parkinsonism manifesting in a female patient due to atypical turner syndrome. Mov Disord 2013;28:675-678. (IF: 5.6)
  8. Rolfs A, Fazekas F, Grittner U, …, Stroke in Young Fabry Patients (sifap) Investigators. Acute cerebrovascular disease in the young: the Stroke in Young Fabry Patients study. Stroke 2013;44:340-349. (IF: 6.0)
  9. Vulinovic F, Lohmann K, Rakovic A, …, Rolfs A, Klein C, Seibler P. Unraveling Cellular Phenotypes of Novel TOR1A mutations. Hum Mutat 2014;35:1114-1122. (IF: 5.1)
  10. Debette S, Kamatani Y, …, Rolfs A, …, Dallongeville J. Common variation in PHACTR1 is associated with susceptibility to cervical artery dissection. Nat Genet 2015;47:78-83. (IF: 29.6)