AMKE CALIEBE

PERSONAL INFORMATION

Position/Title: Research and teaching position, permanent (Institute of Medical Informatics and Statistics)

Address: Christian-Albrechts University of Kiel, Brunswiker Straße 10, Haus V40, 24105 Kiel, Germany

Tel: +49-431-50030711; Fax: +49-431-50030704

@:caliebe@medinfo.uni-kiel.de; www.uni-kiel.de/medinfo/mitarbeiter/caliebe

EDUCATION/POSITIONS

1990-1996 Study of mathematics and physics (Oldenburg, Kiel)

1996-1999 Mathematical thesis (Mathematical Seminar, Kiel University)

2000-2002 Research position in the DFG project “Weighted branching processes and stochastic analysis of divide-and-conquer algorithms” at the Mathematical Seminar, Kiel University

2002-2003 Research and teaching position at the Mathematical Seminar, Kiel University

2003-present Research and teaching position at the Institute of Medical Informatics and Statistics (permanent position), Kiel University

2018 Submission of habilitation thesis (expected completion: November 2019)

ACADEMIC ACTIVITIES

2013-2019 Member of several appointment committees of Kiel University (W2 Statistical Genetics, W2 Medical Informatics, W3 Medical Ethics (Medical Faculty), W3 Probability Theory, W2 Stochastics (Mathematical Seminar))

2014-present Member of the Ethics Committee of the Medical Faculty of Kiel University

2017-present Member of the International Society for Forensic Genetics

2017-present Member of the „DNA Commission on Interpretation of Y-STR Analysis” of the International Society for Forensic Genetics

2018 Organizer of the international workshop „Advanced Statistical and Stochastic Methods in Forensic Genetics”, Cologne University

2018-2019 Guest editor of the journal Human Genetics for the Special Issue „Genetic epidemiology of complex diseases: Impact of population history and modelling assumptions”

2018-present Member of the project group “Biometry in the Ethics Committee” in the GMDS (German Association for Medical Informatics, Biometry and Epidemiology)

AWARDS AND RESEARCH VISITS

1993-1996 German National Merit Foundation (Studienstiftung des deutschen Volkes)

1997-1998 PhD Scholarship (State Schleswig-Holstein)

1999 Research Scholarship of the Federal Ministry of Education and Research (BMBF, Hochschulsonderprogramm III)

2016 Visiting Scholarship of the program „Probability and Statistics in Forensic Science”, Isaac Newton Institute for Mathematical Sciences (England)

2018 Visiting Scholar by invitation of Prof. T. Egeland, Norwegian University of Life Sciences, Oslo (Norway)

2019 Visiting Scholar by invitation of Prof. J. Curran, University of Auckland (New Zealand)

2019 Nominated for the Hensel-Award of the Medical Faculty of Kiel for the best Habilitation in the last five years (3 nominated, decision in December 2019)

SELECTED PUBLICATIONS

From 92 original publications; total citations: 3,186; h-index: 24

    1. Lao O, Lu TT, Nothnagel M, Junge O, Freitag-Wolf S, Caliebe A, Balascakova M, Bertranpetit J, Bindoff LA, Comas D, Holmlund G, Kouvatsi A, Macek M, Mollet I, Parson W, Palo J, Ploski R, Sajantila A, Tagliabracci A, Gether U, Werge T, Rivadeneira F, Hofman A, Uitterlinden AG, Gieger C, Wichmann HE, Rüther A, Schreiber S, Becker C, Nürnberg P, Nelson MR, Krawczak M, Kayser M. Correlation between genetic and geographic structure in Europe. Curr Biol 2008;18:1241-1248. [IF: 9.2]
    2. Flachsbart F, Caliebe A, Kleindorp R, Blanché H, von Eller-Eberstein H, Nikolaus S, Schreiber S, Nebel A. Association of FOXO3A variation with human longevity confirmed in German centenarians. Proc Natl Acad Sci U S A 2009;106:2700-2705. [IF: 9.6]
    3. Caliebe A, Kleindorp R (equally contributing first author), Blanché H, Christiansen L, Puca AA, Rea IM, Slagboom E, Flachsbart F, Christensen K, Rimbach G, Schreiber S, Nebel A. No or only population-specific effect of PON1 on human longevity: a comprehensive meta-analysis. Ageing Res Rev 2010;9:238-244.
      [IF: 10.4]
    4. Flachsbart F, Dose J, Gentschew L, Geismann C, Caliebe A, Knecht C, Nygaard M, Badarinarayan N, ElSharawy A, May S, Luzius A, Torres GG, Jentzsch M, Forster M, Häesler R, Pallauf K, Lieb W, Derbois C, Galan P, Drichel D, Arlt A, Till A, Krause-Kyora B, Rimbach G, Blanché H, Deleuze JF, Christiansen L, Christensen K, Nothnagel M, Rosenstiel P, Schreiber S, Franke A, Sebens S, Nebel A. Identification and characterization of two functional variants in the human longevity gene FOXO3. Nat Commun 2017;8:2063.
      [IF: 11.9]
    5. Knecht C, Mort M, Junge O, Cooper DN, Krawczak M, Caliebe A. IMHOTEP-a composite score integrating popular tools for predicting the functional consequences of non-synonymous sequence variants. Nucleic Acids Res 2017;45:e13. [IF: 11.1]
    6. Slooten K, Caliebe A. Contributors are a nuisance (parameter) for DNA mixture evidence evaluation. Forensic Sci Int Genet 2018;37:116–125. [IF: 4.9]
    7. Krause-Kyora B, Nutsua M, Boehme L, Pierini F, Pedersen DD, Kornell SC, Drichel D, Bonazzi M, Möbus L, Tarp P, Susat J, Bosse E, Willburger B, Schmidt AH, Sauter J, Franke A, Wittig M, Caliebe A, Nothnagel M, Schreiber S, Boldsen JL, Lenz TL, Nebel A. Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans. Nat Commun 2018;9:1569. [IF: 11.9]
    8. Aramillo Irizar P, Schäuble S, Esser D, Groth M, Frahm C, Priebe S, Baumgart M, Hartmann N, Marthandan S, Menzel U, Müller J, Schmidt S, Ast V, Caliebe A, König R, Krawczak M, Ristow M, Schuster S, Cellerino A, Diekmann S, Englert C, Hemmerich P, Sühnel J, Guthke R, Witte OW, Platzer M, Ruppin E, Kaleta C. Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly. Nat Commun 2018;9:327. [IF: 11.9]
    9. Caliebe A, Burger H-U, Knoerzer, D, Kieser, M (2019) Big Data in der klinischen Forschung: Vieles ist noch Wunschdenken. Dtsch Arztebl , 116: A-1534 / B-1266 / C-1246. [IF: 4.5]
    10. Gundlach S, Junge O, Wienbrandt L, Krawczak M, Caliebe A. Comparison of Markov chain Monte Carlo software for the evolutionary analysis of Y-chromosomal microsatellite data. Comput Struct Biotec 2019;17:1082-1090. [IF: 4.7]