ALEKSANDAR RAKOVIC

 

PERSONAL INFORMATION

Position/Title: Research Group Leader (Institute of Neurogenetics), PhD

Address University of Lübeck; Ratzeburger Allee 160, 23538 Lübeck, Germany

Tel: +49-451-2903352; Fax: +49-451-2903355

@:aleksandar.rakovic@neuro.uni-luebeck.de; www.neurogenetics-luebeck.de

 

EDUCATION/POSITIONS

1995-2005 Studies of Biology (University of Belgrade, Belgrade, Serbia)

2006-2007 PhD thesis (Laboratory for Radiobiology and Molecular Genetics, Institute of Nuclear Sciences, Belgrade, Serbia)

2007-2011 PhD thesis (Section of Clinical and Molecular Neurogenetics at the Department of Neurology, University of Lübeck, Germany)

2011   Postdoctoral researcher at the Section of Clinical and Molecular Neurogenetics

2013-present Leader of the research group “Molecular mechanisms of Parkinson disease” (Institute of Neurogenetics, University of Lübeck)

 

AWARDS

2007 Scholarship from Department of Neurology, University of Lübeck, Lübeck, Germany

2007 Scholarship from German Academic Exchange Service (DAAD)

2011 Travel grant from the Movement Disorder Society

2014 Prize for the Best Doctoral Thesis’ in the MINT Section (Mathmatics, Engineering, Natural, and Technical Sciences) of the University of Lübeck

 

SELECTED PUBLICATIONS

From 21 original publications; total citations: 557; h-index: 11

  1. Rakovic A, Grünewald A, Seibler P, …, Klein C. Effect of endogenous mutant and wild-type PINK1 on Parkin in fibroblasts from Parkinson disease patients. Hum Mol Genet 2010;19:3124-3137. (IF: 6.7)
  2. Rakovic A, Grunewald A, Kottwitz J, …, Klein C. Mutations in PINK1 and Parkin impair ubiquitination of Mitofusins in human fibroblasts. PLoS One 2011;6:e16746. (IF: 3.5)
  3. Rakovic A, Grünewald A, Voges L, …, Klein C. PINK1-Interacting Proteins: Proteomic Analysis of Overexpressed PINK1. Parkinsons Dis 2011;153979. (IF: 2.1)
  4. Grünewald A, Arns B, Seibler P, Rakovic A,… , Klein C. ATP13A2 mutations impair mitochondrial function in fibroblasts from patients with Kufor-Rakeb syndrome. Neurobiol Aging 2012;33:1843. (IF: 4.9)
  5. Rakovic A, Shurkewitsch K, Seibler P, …, Klein C. Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: study in human primary fibroblasts and induced pluripotent stem cell-derived neurons. J Biol Chem 2013;288:2223-2237. (IF: 4.6)
  6. Zanon A, Rakovic A (equally contributing first author), …, Pichler I. Profiling of Parkin-binding partners using tandem affinity purification. PLoS One 2013;8:e78648. (IF: 3.5)
  7. Lohmann K, Wilcox RA, Winkler S, …, Rakovic A, …, Klein C. Whispering dysphonia (DYT4 dystonia) is caused by a mutation in the TUBB4 gene. Ann Neurol 2013;73:537-545. (IF: 11.9)
  8. Deuse T, Hua X, Wang D, …, Rakovic A…, Schrepfer S. Dichloroacetate prevents restenosis in preclinical animal models of vessel injury. Nature 2014;509:641-644. (IF: 42.4)
  9. Vulinovic F1, Lohmann K, Rakovic A, … , Seibler P. Unraveling cellular phenotypes of novel TorsinA/TOR1A mutations. Hum Mutat 2014;35:1114-1122. (IF: 5.1)
  10. Rakovic A, Seibler P, Klein C. iPS models of Parkin and PINK1. Biochem Soc Trans 2015;43:302-307. (IF: 3.2)